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Capnomed GmbH nebulizer (capnopen
Nebulizer (Capnopen, supplied by Capnomed GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/nebulizer+(capnopen/nebulizer+capnopen/nct03280511-20-11-13
Average 90 stars, based on 1 article reviews
nebulizer (capnopen - by Bioz Stars, 2026-10
90/100 stars

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Injection:

Article Title: First-line palliative systemic therapy alternated with oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy for unresectable colorectal peritoneal metastases: A single-arm phase II trial (CRC-PIPAC-II).
Article Snippet: Background: Palliative systemic therapy alternated with electrostatic precipitation oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy (ePIPAC) has never been prospectively investigated in patients with unresectable colorectal peritoneal metastases (CPM).. The CRC-PIPAC-II study aimed to assess safety, feasibility and efficacy of such bidirectional therapy.. Methods: This two-center, single-arm, phase II trial enrolled chemotherapy-naïve patients to undergo three treatment cycles, consisting of systemic therapy (CAPOX, FOLFOX, FOLFIRI, or FOLFOXIRI, all with bevacizumab) and oxaliplatin-based ePIPAC (92 mg/m2) with intravenous leucovorin (20 mg/m2) and 5-fluorouracil (400 mg/m2).

Article Title: Enhanced intraperitoneal delivery of charged, aerosolized curcumin nanoparticles by electrostatic precipitation.
Article Snippet: Therapeutic solutions were aerosolized at room temperature by a specific nebulizer (CapnoPen, Capnomed, Zimmern o.R., Germany) connected to a high-pressure angioinjector (Accutron Thera, Medtron, Saarbrücken, Germany).

Article Title: Comparing patient reported abdominal pain between patients treated with oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy (PIPAC-OX) and primary colorectal cancer surgery.
Article Snippet: Oxaliplatin was prepared in a total volume of 150 mL dextrose solution and injected through the nebulizer (CapnoPen, Capnomed GmbH, Villingendorf, Germany) in 5 min, after which the Ultravision generator (Ultravision, Alesi Surgical, Cardiff, UK) administered electrostatic precipitation to the aerosol.

Article Title: Standardizing training for Pressurized Intraperitoneal Aerosol Chemotherapy.
Article Snippet: Furthermore, important practical and safety aspects have been summarized comprehensively(1, 6- 8) Of note, access to the nebulizer (Capnopen®, Capnomed, Albring 81, 78658 Zimmer ob.

Article Title: Nab-PIPAC: a phase IB study protocol of intraperitoneal cisplatin and nab-paclitaxel administered by pressurised intraperitoneal aerosol chemotherapy (PIPAC) in the treatment of advanced malignancies confined to the peritoneal cavity
Article Snippet: Cisplatin 10.5 mg/m2 body surface in 150 ml NaCl 0,9% (concentration of 1mg/ml) and nab-paclitaxel (Abraxane) in 150 ml NaCl 0,9% at escalating doses will be applied sequentially through a nebulizer (Capnopen®, Capnomed GmbH, Villigendorf, Germany) to a high-pressure injector (Accutron HP-D Injecteur, Medtron AG) with a flow rate of 0.6-0.7 ml/s and a median droplet size of 11 (3-15) μm at ambient temperature and at a maximal upstream pressure of 300 psi intraperitoneally.

Article Title: Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) with Oxaliplatin, Cisplatin, and Doxorubicin in Patients with Peritoneal Carcinomatosis: An Open-Label, Single-Arm, Phase II Clinical Trial
Article Snippet: A nebulizer (Capnopen ® , Capnomed, Villingendorf, Germany) was then connected to an intravenous high-pressure injector (Arterion Mark 7 ® , Medrad Healthcare, Germany) and inserted into the abdomen.

Aerosol:

Article Title: First-line palliative systemic therapy alternated with oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy for unresectable colorectal peritoneal metastases: A single-arm phase II trial (CRC-PIPAC-II).
Article Snippet: Background: Palliative systemic therapy alternated with electrostatic precipitation oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy (ePIPAC) has never been prospectively investigated in patients with unresectable colorectal peritoneal metastases (CPM).. The CRC-PIPAC-II study aimed to assess safety, feasibility and efficacy of such bidirectional therapy.. Methods: This two-center, single-arm, phase II trial enrolled chemotherapy-naïve patients to undergo three treatment cycles, consisting of systemic therapy (CAPOX, FOLFOX, FOLFIRI, or FOLFOXIRI, all with bevacizumab) and oxaliplatin-based ePIPAC (92 mg/m2) with intravenous leucovorin (20 mg/m2) and 5-fluorouracil (400 mg/m2).

Article Title: Enhanced intraperitoneal delivery of charged, aerosolized curcumin nanoparticles by electrostatic precipitation.
Article Snippet: Therapeutic solutions were aerosolized at room temperature by a specific nebulizer (CapnoPen, Capnomed, Zimmern o.R., Germany) connected to a high-pressure angioinjector (Accutron Thera, Medtron, Saarbrücken, Germany).

Article Title: Comparing patient reported abdominal pain between patients treated with oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy (PIPAC-OX) and primary colorectal cancer surgery.
Article Snippet: Oxaliplatin was prepared in a total volume of 150 mL dextrose solution and injected through the nebulizer (CapnoPen, Capnomed GmbH, Villingendorf, Germany) in 5 min, after which the Ultravision generator (Ultravision, Alesi Surgical, Cardiff, UK) administered electrostatic precipitation to the aerosol.

Article Title: Standardizing training for Pressurized Intraperitoneal Aerosol Chemotherapy.
Article Snippet: Furthermore, important practical and safety aspects have been summarized comprehensively(1, 6- 8) Of note, access to the nebulizer (Capnopen®, Capnomed, Albring 81, 78658 Zimmer ob.

Article Title: Nab-PIPAC: a phase IB study protocol of intraperitoneal cisplatin and nab-paclitaxel administered by pressurised intraperitoneal aerosol chemotherapy (PIPAC) in the treatment of advanced malignancies confined to the peritoneal cavity
Article Snippet: Cisplatin 10.5 mg/m2 body surface in 150 ml NaCl 0,9% (concentration of 1mg/ml) and nab-paclitaxel (Abraxane) in 150 ml NaCl 0,9% at escalating doses will be applied sequentially through a nebulizer (Capnopen®, Capnomed GmbH, Villigendorf, Germany) to a high-pressure injector (Accutron HP-D Injecteur, Medtron AG) with a flow rate of 0.6-0.7 ml/s and a median droplet size of 11 (3-15) μm at ambient temperature and at a maximal upstream pressure of 300 psi intraperitoneally.

Article Title: Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) with Oxaliplatin, Cisplatin, and Doxorubicin in Patients with Peritoneal Carcinomatosis: An Open-Label, Single-Arm, Phase II Clinical Trial
Article Snippet: A nebulizer (Capnopen ® , Capnomed, Villingendorf, Germany) was then connected to an intravenous high-pressure injector (Arterion Mark 7 ® , Medrad Healthcare, Germany) and inserted into the abdomen.



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